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Stanozolol

 

Stanozolol (also referred to by its brand name Winstrol) is a synthetic anabolic and androgen steroid used medically to treat hormone deficiencies and certain blood disorders, more commonly referred to as Winstrol.

Medical uses

 

 

 

 

Non-medical uses

 

Bodybuilders and athletes frequently utilize these substances to increase muscle mass, enhance strength, and extend endurance - often leading to doping violations in sports.

Side effects

 

 

 

 

 

 

Pharmacology

Pharmacodynamics

 

Binds to androgen receptors to promote protein synthesis. Due to structural modifications, its androgenic activity is reduced compared to that of testosterone.

Pharmacokinetics

 

 

 

 

 

Chemistry

Synthesis

 

Synthesized in 1960s through modification of dienones. Key intermediate involves cyclization of stanozolone derivatives.

Detection in body fluids

 

 

 

 

History

 

Developed by Winthrop Laboratories in 1962. Approved by FDA in 1967 under brand name Winstrol.

Society and culture

Generic names

 

 

 

 

Brand names

 

 

 

 

Legal status

 

Scheduled as a Schedule III controlled substance under CSA for anabolic steroid regulations. Requires prescription.

Doping in sports

 

Banned by World Anti-Doping Agency (WADA) since inception of prohibited list. Sanctioned athletes face disqualification and suspensions.

Research

 

Investigated for potential use in treating muscle-wasting conditions. Studies explore its role in pediatric growth disorders with caution due to side effects.

References

 

 

 

 



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